Smallest Organism; Highest Threat - Zdravlje, medicina, lijecenje, zdravstveni portal

Smallest Organism; Highest Threat

Smallest Organism; Highest Threat
Amit Pant, Rupesh Chikhale, Pankaj Wadibhasme, Sunil Menghani, Pramod Khedekar
Mat Soc Med. 2012; 24(4): 268-273

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Abstract

Ever since the discovery of virus in beginning of 20th century, infections caused by these organisms have captured attention of researchers. The evolution of viruses is still a controversy, even same for their categorization in either living or non-living. It is clear that besides many controversies virus remains challenging to treat as well as to control in some extent. Though vaccines are available as prophylactic tool and antiviral drugs for treatment, still virus exist in host cells if they successfully invade biological machinery. Now it remains as challenge to treat these smallest organisms with high degree of efficacy and safety. To answer the demand of the present world there is urgent need of more potent and novel drugs for treatment and vaccines to prevent infection. Answer to this problem will definitely reduce casualties occurring worldwide. This review presents few of the pandemics, their causative agents, current status of treatment and future prospective.

REFERENCES

1. Randles J, Ogle H. Viruses and viroids as agents of plant disease. Plant Pathogens and Plant Diseases. Brown JF, Ogle HJ editor. Australia: Rockvale Publication: 1997. p. 104-26.

2. Wobus CE, Nguyen TH. Viruses are everywhere — what do we do? Current Opinion in Virology 2012; 2:60–2.

3. Liu S, Vijayendran D, Bonning BC. Next generation sequencing technologies for insect virus discovery. Viruses 2011; 3:1849-69.

4. Virology blog: Racaniello V. Discovery of viruses. 23rd December 2008. Available from: http://www.virology.ws/2008/12/23/discovery-of-viruses. Assessed 09 August 2012.

5. Koonin EV, Senkevich TG, Dolja VV. The ancient virus world and evolution of cells. Biology Direct 2006; 1:29.

6. Rhodes AJ. Recent advances in virus infections: the new era in virology. British Medical Journal. London Saturday April 9 1960; 1071-77

7. Bandea CI. The origin and evolution of viruses as molecular organisms. Nature Preceding. hdl: 10101/npre. 2009. 3886.1: Posted 21 Oct 2009.

8. Gelderblom HR. Structure and classification of viruses. In: Baron, S., editor. Medical Microbiology. 4th edition. 1996, University of Texas Medical Branch at Galveston. Available from: http://www.ncbi.nlm.nih.gov/books/NBK8174/. Assessed on August, 2012.

9. Leiman PG, Kanamaru S, Mesyanzhinov VV, Arisaka F, Rossmann MG. Structure and morphogenesis of bacteriophage T4. CMLS Cellular and Molecular Life Sciences 2003; 60: 2356–70.

10. Villarreal LP. Are Viruses Alive? Scientific American, Inc.102 Scientific American December 2004. Available on free database from: w w w. s c i a m . c o or available on free database from: mhttp://scidiv.bellevuecollege.edu/bron/Bio%20211%20Web%20S09/password%20211/VirusesAlive%20Villarreal%2004.pdf

11. Forterre P. New hypotheses about the origins of viruses, prokaryotes, and eukaryotes. Frontiers of Life, Van TT, Mounolou JK, Shneider J, Mc Kay C. editor Editions Frontieres. Gif-sur-Yvette Cedex, France 1992; 221–34.

12. Forterre P. The origin of viruses and their possible roles in major evolutionary transitions. Virus Res 2006; 117(1): 5-16.

13. Carter JB. Saunders VA. Viruses and their importance. Virology: Principles and Applications. John Wiley & Sons, Ltd. 2007; 1-8.

14. Bubanovic I. Najman S. Andjelkovic Z. Origin and evolution of viruses: Escaped DNA/RNA sequences as evolutionary accelerators and natural biological weapons. Medical Hypotheses 2005; 65: 868–72.

15. Poole1 AM. Penny D. Evaluating hypotheses for the origin of eukaryotes. BioEssays 2006; 29:74–84.

16. Mahy BWJ, Van Regenmortel MHV. Desk Encyclopaedia of General Virology. Academic Press, Jordan Hill, Oxford, UK 2010; 1-107

17. Huang CR, Lo SJ. Evolution and Diversity of the Human Hepatitis D Virus Genome. Advances in Bioinformatics Volume 2010; Article ID 323654, 1-9.

18. Yozwaik N. How did viruses evolve from a universal common ancestor? Ask A Scientist. HHMI bulletin. May 2011; 45.

19. Makałowska I, Rogozin IB, Makałowski W. Genome Evolution. Advances in Bioinformatics Volume 2010; Article ID 643701: 1-2.

20. Krupovic M, Ravantti JJ, Bamford DH. Geminiviruses: a tale of a plasmid becoming a virus. BMC Evolutionary Biology 2009; 9:112.

21. Fraser CM. The Merck Veterinary Manual. Pharmacology: Antiviral Agents and Biologic Response Modifiers: Introduction. Available from www.merckvetmanual.com/mvm/index. Assessed on 10 August, 2012.

22. Jain S, Vyas RK, Pandit P, Vyas S. A review on fate of antiviral drugs in environment and detection techniques. International Journal of Environmental Sciences 2011; 1(7): 1526-41.

23. English JP. The chemotherapy of infectious disease, 1909-1959. Journal of Chemical Education. April 1960; 37(4) : 172-77.

24. Holmes EC. Evolutionary history and phylogeography of human viruses. Annual Review of Microbiology. 2008; 62: 307–28.

25. Levy JA. Discovery, structure, heterogeneity, and origins of HIV. HIV and the pathogenesis of AIDS. Third edition, Washington, D.C: ASM Press, 2007: 1-26.

26. UNAIDS database. Fast facts about HIV. UNAIDS: Joint United Nations Programme on HIV/ AIDS. Available on http://www.unaids.org. Assessed on August, 2012.

27. Scherer E, Douek D, Mc Michael A. 25 years of HIV research on virology, virus restriction, immunepathogenesis, genes and vaccines. British Society for Immunology, Clinical and Experimental Immunology 2008; 154: 6–14.

28. Montagnier L, Chermann JC, Rey F, Nugeyre MT, Chamaret S, Gruest J, D, et al. Isolation of a T-Lymphotropic retrovirus from a patient at risk for Acquired Immune Deficiency Syndrome (AIDS). Science, New Series, May 20, 1983; Vol. 220, No. 4599: 868-71.

29. Weiss RA. Special Anniversary Review: Twenty-five years of human immunodeficiency virus research: successes and challenges. British Society for Immunology, Clinical and Experimental Immunology 2008; 152: 201–210.

30. World Health Organization Data Base: Global Health Observatory (GHO)–HIV/AIDS. World Health Organization 2012. Available on www.who.int. Assessed on August 2012.

31. Media centre: HIV/AIDS Fact sheet No 360, July 2012. World Health Organization 2012. Available from http://www.who.int/mediacentre/factsheets/fs360/en/index.html. Assessed on August 2012.

32. Global Health Observatory (GHO): World health statistics 2012. World Health Organization 2012. Available from www.who.int/gho/publications/world_health_statistics/2012/en/. Assessed on August 2012.

33. Annual Report 2010-11. Department of AIDS Control National AIDS Control Organisation Ministry of Health & Family Welfare Government of India. Available from http:\\nacoonline.org. Assessed on August 2012.

34. National Aids Control Programme: Response to the HIV Epidemic in India. Department of AIDS Control National AIDS Control Organisation Ministry of Health & Family Welfare Government of India. Available on http:\\nacoonline.org. Assessed on August 2012.

35. Zuckerman AJ. Hepatitis Viruses. In: Baron, S., editor. Medical Microbiology. 4th edition. 1996, University of Texas Medical Branch at Galveston. Available in http://www.ncbi.nlm.nih.gov. Assessed on August, 2012.

36. Epidemiology and Prevention of Vaccine-Preventable Diseases. The Pink Book: Course Textbook. 12th Edition, (2 pt) 115-138.

37. Hepatitis B Fact sheet No 204, July 2012. World Health Organization 2012. Available from: http://www.who.int/mediacentre/factsheets/fs204/en/index.html. Assessed on August 2012.

38. Weekly epidemiological record. 2 October, 2009, 84th year, No. 40. 2009; 84: 405–420.

39. Datta S. An overview of molecular epidemiology of hepatitis B virus (HBV) in India. Virology Journal 2008, 5:156-167.

40. Averhoff FM, Glass N, Holtzman D. Global Burden of Hepatitis C: Considerations for Healthcare Providers in the United States. Clinical Infectious Diseases 2012; 55(S1): S10–15.

41. Global Alert and Response (GAR). Hepatitis C- Surveillance and Control. Available on http://www.who.int/csr/disease/hepatitis/whocdscsrlyo2003/en/index4. Assessed on Aug 2012.

42. Influenza Vaccine Information Statement. U.S Department of Health and Human Services- Centre for Disease Control and Prevention. Available from: www.cdc.gov/vaccinesafety/Activities/Activities. Assessed on August 2012.

43. Influenza Vaccination Coverage among Pregnant Women — 29 States and New York City, 2009–10 Season. Centers for Disease Control and Prevention- Morbidity and Mortality Weekly Report (MMWR). Weekly / Vol. 61 / No. 7 February 24, 2012.

44. Rao BL. Epidemiology and control of influenza. The National Medical Journal of India 2003. 16 (3): 143-149.

45. Hay AJ, Gregory V, Douglas AR, Lin YP. The evolution of human influenza virus. Philosophical Transactions of the Royal Society. Series B: Biological Sciences. 2001. 356: 1861-70.

46. Media centre Influenza (Seasonal) Fact sheet No. 211, April 2009. World Health Organization 2012. Available from http://www.who.int/mediacentre/factsheets/fs211/en/index.html. Assessed on August 2012.

47. Measles, Mumps & Rubella- Frequently Asked Questions. National Immunization Advisory Committee Royal College of Physicians of Ireland. March 2002.

48. Measles Fact Sheet. Epidemiological Unit. Ministry of Healthcare and Nutrition. 231, De Saram Place, Colombo 10.

49. Dr. Brundtland GH. Six diseases cause 90% of infectious disease deaths. Removing Obstacles to Healthy Development. WHO Report on Infectious Diseases. World Health Organization 1999.

50. Measles Fact sheet No. 286. April 2012. World Health Organization 2012. Available from: http://www.who.int/mediacentre/factsheets/fs286/en/index.html. Assessed on August 2012.

51. Sinha K. Times of India report: 47% of global measles deaths in India. Apr 24, 2012.

52. Atkinson W. Hamborsky J. Wolfe S. eds. Centers for Disease Control and Prevention. Epidemiology and Prevention of Vaccine-Preventable Diseases. 12th ed., second printing. Washington DC: Public Health Foundation 2012: 275-90.

53. Rubella Fact sheet No. 367. July 2012. World Health Organization 2012. Assessed on August 2012.

54. The epidemiologic and clinical basis of rubella surveillance. Measles and Rubella Surveillance and Outbreak Investigation Guidelines. World Health Organization, Regional Office for South-East Asia. 2009. 57-64.

55. Dewan P, Gupta P. Burden of Congenital Rubella Syndrome (CRS) in India. Indian Pediatrics Volume 49. May 16, 2012. 377-99.

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