Comparing Two Techniques of Panretinal Photocoagulation on Visual Acuity on Patients with Proliferative Diabetic Retinopathy - Zdravlje, medicina, lijecenje, zdravstveni portal

Comparing Two Techniques of Panretinal Photocoagulation on Visual Acuity on Patients with Proliferative Diabetic Retinopathy

Comparing Two Techniques of Panretinal Photocoagulation on Visual Acuity on Patients with Proliferative Diabetic Retinopathy
Zeljko Kovacic, Milan Ivanisevic, Lovro Bojic, Zlatko Hrgovic, Mladen Lesin, Deni Kurelovic
Med Arh. 2012; 66(5): 321-323

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We wanted to examine which of two panretinal photocoagulation (PRP) techniques, classical panretinal photocoagulation (CPRP) and modifield peripheral panretinal photocoagulation PPRP), causes less decline of visual acuity (VA) due to macular edema (ME) in patients with proliferative diabetic retinopathy (PRD). This clinical study includes 180 eyes with PDR with initial papillar neovascularization. The patients were divided into two groups according the RP. PPRP and CPRP showed the decline of VA in all patients, more pronounced in the CPRP group after one week. After three and six months, with CPRP and PPRP the values of VA was stabilized. The result suggests that eyes with PDR and starting epipapillar neovascularisation should be treated with PPRP with priority given to CPRP because it caused better VA.


1. Klein R, Klein BEK, Moss SE. Epidemiology of proliferative diabetic retinopathy. Diabetes Care. 1992; 15: 1875-1891.

2. Klein R. Prevention of visual loss from diabetic retinopathy. SURV Ophthalmol. 2002; 47: 266-272.

3. Gardner TW, Eller AW, Friberg TR, Reduction of severe macular edema in eyes with poor vision after panretinal photocoagulation for proliferative diabetic retinopathy. Graefes Arch Clin Exp Ophthalmol. 1991; 229: 323-328.

4. Margolis R, Singh RP, Bhatnager P, Kaiser PK. Intravitreal triamcinolone as adjuction treatment to laser panretinal photocoagulation for concomitant proliferative diabetic retinopathy and clinically significant macular edema. Acta Ophthalmol. 2008; 86: 105-110.

5. Maia O Jr, Akahasy Wy, Bonamoni MT, Marbach Rf, Kara-Jose N. Visual stability in diabetic rethinopathy treated by panretinal laser photocoagulation. Arq Bras Endocrinol Metabol. 2007; 51: 575-580.

6. Shimura M, Yasuda K, Nakazawa T, Tamai M. Visual disfunction after panretinal photocoagulation in patients with severe diabetic retinopathy an good vision. Am J Ophthalmol. 2005; 140: 8-15.

7. Diabetic Retinopathy Study Research Group. Photocoagulation treatment of proliferative diabetic retinopathy: Clinical application of Diabetic Retinopathy Study (DRS) findings, DRS report No. Invest Ophthalmol Vis Sci. 1981; 88: 583-600.

8. Early treatment diabetic retinopathy study research group: Early photocoagulation for diabetic retinopathy, ETDRS report No 9. Ophthalmology. 1991; 98 (Suppl): 765-85.

9. Čupak K, Laktić N, Padovan S. Primjena argonskog lasera u nekih vaskularnih bolesti mrežnice. In: Čupak K, Ed. Fotokoagulacija. Laser u oftalmologiji. Čakovec: Zrinjski, 1979: 40-49.

10. Pournaras CJ, Tsacopoulos M, Strommer K, Gilodi N, Levenberger PM. Scatter photocoagulation restores tissue hypoxia in experimental vasoproliferative microangiopathy on miniatures pigs. Ophthalmology. 1990; 97: 1329-1333.

11. American Academy of Ophthalmology. Retina and vitreus. Basic clinical science course 1993-4, section 12, San Francisco: AAO; 1993: 61.

12. Zein WM, Noureddin BN, Jurdi FA, Schakal A, Bashshur ZF. Panretinal photocoagulation and intravitreal triamciolone acetonide for the management of proliferative diabetic retinopathy with macular edema. Retina. 2006; 26: 137-142.

13. Lee CM, Olk RJ, Akduman L.Continued modifield grid and panretinal hotocoagulation for diabetic macular edema and proliferative diabetic retinopathy. Ophthalmic Surq Lasers. 2000; 31: 292-300.

14. Wei ZY, Hu SH, Tang N, Wn J, Wang J. Effect of argon laser photocoagulation on diabetic retinopathy. Ci Yi Jun Da Xue Xue Bao. 2004; 24: 1313-1315.

15. Walczynski M, Dzivqielewski K. Result of laser photocoagulation in patients with diabetic retinopathy developed as a complication of diabetes type 2. Klin Oczna. 2006; 108: 66-69.

16. McDonald Hr, Schatz H. Macular edema following panretinal photocoagulation Retina. 1985; 5: 5-10.

17. Davis MD. Proliferative diabetic retinopathy. U: Ryan SJ, ur. Retina. 2. ed. St Luis: CV Mosby Co, 1994: 1319-1359.

18. Štriga M, Katušić D. Traumatic lesion and complications after argon laser photocoagulation treatment of diabetic retinopathy. Diab Croat. 1990; 19: 87-98.

19. ŠtrigaM, Katušić D, Ćurković T. Functional lesions and results following argon laser treatment for diabetic retinopathy. Diab Croat. 1990; 19: 99-108.

20. McDonald Hr Schatz H. Visual loss following panretinal photocoagulation for roliferative diabetic retinopathy. Ophthalmology. 1985; 92: 388-393.

21. Ferris FL, Podgor MJ, Davis MD. Macular edema in diabetic retinopathy study atients. Diabetic retinopathy study report number 12. Ophthalmology. 1987; 94: 754-760.

22. Meyers SM. Macular edema after scatter photocoagulation for proliferative diabetic retinopathy. Am J Ophthalmol. 1980; 90: 210-216.

23. Aylward GW, Pearson RV, Jagger JD, Hamilton AM. Extensive argon laser photocoagulation in treatment of proliferative diabetic retinopathy. Br J Ophthalmol. 1989; 73: 197-201.

24. Zhang CF. Clinical study on preproliferative and proliferative diabetic retinopathy. Chung Kuo I Hsueh Ko Hsueh Yuan Hseueh Pao. 1989; 11: 224-225.

25. Blankenship GW. A clinical comparison of central and peripheral argon laser panretinal photocoagulation for proliferative diabetic retinopathy. Ophthalmology. 1988; 95: 170-177.

26. Vine AK. The efficacy of additional argon laser photocoagulation for persistent, severe proliferative diabetic retinopathy. Ophthalmology. 1985; 92: 1532-1537.

27. Wade Ec, Blankenship GW. The effect of short versus long exposure times of argon laser panretinal photocoagulation on proliferative diabetic retinopathy. Graefes Arch Clin Exp Ophthalmol. 1990; 228: 226-231.

28. Odonoghue HN. Laser treatment in diabetic retinopathy. Trans Ophthalmol Soc U K. 1982; 102: 468-470.

29. Zhang CF. Laser treatment for pre-proliferative and proliferative diabetic retinopathy. Chung Hua Yen Ko Tsa Chih. 1989; 24: 329-332.

30. Prskavec FH, Fulmek R, Kleman C, Stelzer N. Changes in the visual field and dark adaptation following panretinal photocoagulation in diabetic retinopaphy. Klin Monatsbl Augenheilkd. 1986; 189: 385-387.

31. Fine SL, Patz A. Ten years after Diabetic Retinopathy Study. Ophthalmology. 1987;94: 739-740.

32. Doft BH, Blankenship GW. Retinopathy risk factor regression after laser photocoagulation for proliferative diabetic retinopathy. Ophthalmology. 1984; 91: 1453-1457.

33. Asher R, Hunt S, Hamilton AM, Townsend C. Photocoagulation for optic disc new vessels in diabetic mellitus. Int Ophthalmol.z1981; 3: 79-85.

34. Lim As, Khoo CY, Ang BC, Chiang C. Argon laser photocoagulation in diabetic retinopathy: five years review of 697 treated eyes. Ann Acad Med Singapore. 1985; 14: 252-260.

35. Atmaca LS, Idil A, Gunduz K. Dye laser treatment in proliferative diabetic retinopathy and maculopathy. Acta Ophthalmol Scand. 1995; 73: 303-307.

36. Bailey CC, Sparrow IM, Grey RH, Cheng H. The national diabetic retinopathy laser treatment audit. III. Clinical outcomes. Eye. 1999; 13: 151-159.

37. Singer DE, Nathan DM, Fogel HA, Schachat AP. Screening for retinopathy. Ann Intern Med. 1992; 116: 660-671.

38. Khosla PK, Gupta V, Tewari HK, Kumar A. Automated perimetric changesfollowing panretinal photocoagulation in diabetic retinopathy. Ophtalmic Surg 1993;24:256-61.

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