Mortality After Acute Myocardial Infarction: Significance of Cardiovascular Diabetic Autonomic Neuropathy (CDAN) - Zdravlje, medicina, lijecenje, zdravstveni portal

Mortality After Acute Myocardial Infarction: Significance of Cardiovascular Diabetic Autonomic Neuropathy (CDAN)

Mortality After Acute Myocardial Infarction: Significance of Cardiovascular Diabetic Autonomic Neuropathy (CDAN)

Snezana Vujosevic, Miroslava Zamaklar, Natasa Belada, Sinisa Stamatovic

Med Arh. 2012; 66(5): 296-299

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Abstract

The aim of this study was to compare intrahospital and long-term mortalities after more than 10 years of the follow up after the first acute myocardial infarction (AMI) with patients with and without CDAN and without diabetes mellitus (DM). Methods: The study was based on 76 (43 men and 33 women) with DM type 2, CDAN was detected in 51 patients, and 374 (295 men and 79 women) without DM consecutively hospitalized with the first-ever AMI from January 1998. to December 2000. in Clinical Center of Montenegro Podgorica. Patients were followed until December 31. 2011. CDAN was searched for by standardized five tests evaluating heart rate and blood pressure variations. Results: Intrahospital mortality was presented in 10. 53 % diabetic patients and 5. 61 % nondiabetic patients, this difference is significant (p=0.048). Long-term mortality was presented at 24 (82. 75%) patients with CDAN and 5 (17. 25%) patients without CDAN (p=0.029). Long term mortality rate was significantly higher in diabetic patients 29 (42. 64 %) than in nondiabetic patients 102 (30. 72 %) (p=0.012). Conclusion: Intrahospital mortality was significantly higher in diabetic than in nondiabetic patients. Identically the mortality after more than 10 years of the follow up after the first AMI was significantly higher in diabetic with, than in diabetic patients without CDAN, as in diabetic than in nondiabetic patients.

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